Task your little mathematicians to crack the code of subtracting 2-digit numbers from 4-digit numbers without regrouping with this fun worksheet. It is important for students to understand the basic relationship among digits in the numbers they are subtracting. When students subtract multi-digit numbers, they subtract digits at the same places to get the difference. Subtract 2-digit numbers from 4-digit numbers without regrouping worksheet provides plenty of practice with this concept.